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A Research Group Is Studying a New Biomarker for Prostate

Question 186

Multiple Choice

A research group is studying a new biomarker for prostate cancer screening in a random sample of asymptomatic men >50 years of age.  As the majority of prostate cancers are slowly progressive, the investigators are concerned that the benefits of the new screening tool will be overestimated due to detection of a disproportionate number of slowly progressive, benign cases.  The research group is most likely concerned about the presence of which of the following types of bias?


A) Hawthorne effect
B) Lead-time bias
C) Length-time bias
D) Observer bias
E) Sampling bias

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