A 65-Year-Old Man Comes to the Office Due to Multiple

A 65-year-old man comes to the office due to multiple hand lesions.  Pink, white, and gray spots have been present on his hands for several years and are slowly increasing in number and size.  The lesions do not itch or hurt.  Medical and family histories are unremarkable.  The patient takes no medications.  BMI is 27 kg/m².  Skin examination of the right hand is shown in the exhibit, and the left hand has similar lesions.  This patient is at greatest risk of developing which of the following?

A) Cutaneous basal cell carcinoma
B) Cutaneous squamous cell carcinoma
C) Inflammatory arthritis
D) Pulmonary hypertension
E) Visceral malignancy

Correct Answer:

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