A Randomized Study Assigned Patients with Sickle Cell Anemia and Silent

A randomized study assigned patients with sickle cell anemia and silent stroke to either monthly transfusion therapy (transfusion group of 110 patients) or usual care (observation group of 105 patients) .  An excerpt of the study results is provided below: Which of the following adverse event estimates is most subject to selection bias?

A) Acute chest syndrome
B) Avascular hip necrosis
C) Headache
D) Iron overload
E) Vasoocclusive pain

Correct Answer:

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