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A 2-Day-Old Boy Is Evaluated in the Newborn Nursery for Jaundice

Question 422

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A 2-day-old boy is evaluated in the newborn nursery for jaundice.  He was born to a 24-year-old primigravid woman who is in good health.  The mother consumed a well-balanced diet and took prenatal vitamins throughout the pregnancy.  The infant is breastfeeding poorly, with a weak latch and suck.  On examination, the patient has jaundice, scleral icterus, a large tongue, and a hoarse cry.  His tone is normal but his activity is decreased.  Laboratory results are as follows: A 2-day-old boy is evaluated in the newborn nursery for jaundice.  He was born to a 24-year-old primigravid woman who is in good health.  The mother consumed a well-balanced diet and took prenatal vitamins throughout the pregnancy.  The infant is breastfeeding poorly, with a weak latch and suck.  On examination, the patient has jaundice, scleral icterus, a large tongue, and a hoarse cry.  His tone is normal but his activity is decreased.  Laboratory results are as follows:   Which of the following is the most likely cause of this infant's condition? A) Defective synthesis of thyroxine B) Iodine deficiency (endemic goiter)  C) Panhypopituitarism D) Thyroid dysgenesis E) Transplacental TSH-receptor antibody Which of the following is the most likely cause of this infant's condition?


A) Defective synthesis of thyroxine
B) Iodine deficiency (endemic goiter)
C) Panhypopituitarism
D) Thyroid dysgenesis
E) Transplacental TSH-receptor antibody

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