A 58-Year-Old Woman Undergoing Systemic Chemotherapy for Advanced Breast Cancer

A 58-year-old woman undergoing systemic chemotherapy for advanced breast cancer with metastases to bone comes to the office for routine follow-up.  She has mild, vague bone pain that is relieved by the occasional use of acetaminophen.  Physical examination shows a well-healed mastectomy scar on the right and a palpable right supraclavicular lymph node.  Mucous membranes are moist.  Laboratory results are as follows: Which of the following is the best next step in management of this patient?

A) Bisphosphonate therapy
B) Corticosteroid therapy
C) Loop diuretics
D) Opioid therapy
E) Radiation therapy

Correct Answer:

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