A 40-Year-Old Man Is Found to Have Severe Hypertriglyceridemia on Routine

A 40-year-old man is found to have severe hypertriglyceridemia on routine evaluation.  He has no present complaints.  Medical history includes hypertension controlled with hydrochlorothiazide and asymptomatic gallstones.  His father had a nonfatal myocardial infarction at age 47.  The patient does not smoke or consume alcohol.  Blood pressure is 130/75 mm Hg and pulse is 70/min.  He is prescribed niacin for his hypertriglyceridemia.  The patient returns 1 week later due to intense, generalized pruritus and flushing.  What is the most likely cause of his complaint?

A) Hypersensitivity reaction
B) Prostaglandin-related reaction
C) Drug-drug interaction
D) Drug-induced vasoconstriction
E) Psychogenic reaction

Correct Answer:

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