A 40-Year-Old Man Comes to the Office for an Annual

A 40-year-old man comes to the office for an annual checkup.  The patient has gained weight over the past year, which he attributes to a diet consisting primarily of processed food and red meat.  He is otherwise asymptomatic and feels well.  Medical history is significant for celiac disease, type 2 diabetes mellitus, hyperlipidemia, and a Wilms tumor treated 35 years ago with chemoradiation and surgical resection.  Medications include insulin, aspirin, and simvastatin.  There is no family history of colon cancer.  Vital signs are normal.  BMI is 48 kg/m².  Examination shows acanthosis nigricans but is otherwise normal.  Which aspect of this patient's history warrants colon cancer screening earlier than what is typically recommended for the general population?

A) Aspirin use
B) Celiac disease
C) Diabetes mellitus
D) History of abdominal radiation therapy
E) Obesity
F) Red meat consumption

Correct Answer:

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