A Study Is Conducted to Standardize Laboratory Equipment in a Hospital

A study is conducted to standardize laboratory equipment in a hospital network.  In one hospital, 2 healthy volunteers undergo testing.  Both are found to have a serum creatinine level of 1.1 mg/dL.  Glomerular filtration rate is estimated using the same equation and reveals values of 118 mL/min in one volunteer and 70 mL/min in the other.  A difference in which of the following parameters best explains the observed laboratory findings in these volunteers?

A) Basal metabolic rate
B) Dietary purine intake
C) Hepatic synthetic function
D) Renal tubular reabsorption capacity
E) Skeletal muscle mass

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