A 46-Year-Old Man Develops Episodes of "Dizzy Spells" Accompanied by Palpitations

A 46-year-old man develops episodes of "dizzy spells" accompanied by palpitations and sweating during exercise.  His symptoms improve after drinking orange juice or eating a protein bar.  The patient was diagnosed with type 2 diabetes 6 months ago and advised to lose weight with dietary modification and exercise.  Since then, he has been working out intensively and has lost 10 kg (22 lb) .  Which of the following mechanisms is responsible for this patient's symptoms when exercising?

A) Decreased hepatic glucose production
B) Increased glucokinase activity
C) Increased glucose-6-phosphatase activity
D) Translocation of glucose transporter 2 to the cell membrane
E) Translocation of glucose transporter 4 to the cell membrane

Correct Answer:

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