A 48-Year-Old Man Comes to the Office Due to Several

A 48-year-old man comes to the office due to several hours of severe right knee pain.  The patient has a history of peptic ulcer disease and gastroesophageal reflux disease.  His right knee is swollen, erythematous, and tender.  Arthrocentesis is performed and synovial fluid analysis shows needle-shaped, negatively birefringent crystals with many neutrophils.  The medication given to this patient selectively binds to an interleukin-1 inducible enzyme that is highly expressed by inflammatory cells and undetectable in the surrounding normal tissue.  Which of the following is most likely the drug used in this patient's treatment?

A) Aspirin
B) Celecoxib
C) Colchicine
D) Infliximab
E) Prednisone

Correct Answer:

Verified

Unlock this answer now
Get Access to more Verified Answers free of charge

Access For Free