A 31-Year-Old Man Is Hospitalized After Sustaining Multiple Injuries During

A 31-year-old man is hospitalized after sustaining multiple injuries during a motor vehicle collision.  The patient is not conscious initially, and no information is available regarding his medical history.  Two days after initial hospitalization, he experiences palpitations and difficulty sleeping.  Shortly thereafter, the patient suffers a generalized tonic-clonic seizure.  When he recovers, he tells the physician that he usually takes medications for anxiety, bipolar disorder, and chronic low back pain.  Temperature is 36.7 C (98.1 F) , blood pressure is 129/82 mm Hg, pulse is 92/min, and respirations are 14/min.  He appears anxious, tremulous, and diaphoretic.  Withdrawal from which of the following medications is the most likely explanation for this patient's presentation?

A) Lamotrigine
B) Lithium
C) Lorazepam
D) Oxycodone
E) Quetiapine
F) Sertraline
G) Valproate

Correct Answer:

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