A 7-Year-Old Boy Is Evaluated for Fatigue

A 7-year-old boy is evaluated for fatigue.  For the last year, he has been avoiding any significant outdoor activities with his peers due to poor energy and shortness of breath.  He also describes occasional pounding in the chest.  Physical examination shows a holosystolic murmur best heard at the lower sternal border.  Echocardiography reveals apical displacement of the tricuspid valve leaflets, decreased right ventricular volume, and atrialization of the right ventricle.  Moderate to severe tricuspid regurgitation is also present.  If this patient's diagnosis is due to a side effect of a drug taken during pregnancy, his biological mother most likely had which of the following conditions?

A) Alcohol use disorder
B) Bipolar disorder
C) Cocaine use disorder
D) Down syndrome
E) Epilepsy
F) Gestational diabetes
G) Hypothyroidism
H) Opioid use disorder
I) Schizophrenia

Correct Answer:

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