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A 52-Year-Old Man Is Evaluated for Low-Grade Fever, Malaise, Abdominal

Question 82

Multiple Choice

A 52-year-old man is evaluated for low-grade fever, malaise, abdominal pain, and diarrhea.  The patient underwent a cadaveric renal transplant 6 months ago to treat renal failure from underlying polycystic kidney disease.  He takes maintenance immunosuppressive therapy.  Physical examination shows mild tenderness in the lower abdominal quadrants with no rebound tenderness.  Serum immunosuppressant levels are within therapeutic range, and renal function studies are normal.  Colonoscopy reveals mucosal erythema and ulcerations.  Biopsy shows large cells with inclusion bodies, and a polymerase chain reaction-based test detects viral DNA.  First-line therapy for the infection is initiated.  This patient is at greatest risk of which of the following from the treatment?


A) Hepatitis
B) Myopathy
C) Neutropenia
D) Pancreatitis
E) Thyroiditis

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