A 12-Year-Old Boy Has Prolonged Oral Bleeding Immediately After a Tooth

A 12-year-old boy has prolonged oral bleeding immediately after a tooth extraction.  Despite several interventions, the bleeding persists for hours and stops only after desmopressin (DDAVP) administration.  The patient has several dental caries due to excessive juice intake and inconsistent oral hygiene.  He has no other medical problems and takes no medications.  His father and paternal grandmother have also had excessive bleeding after dental procedures.  Review of systems is positive for mild bruising on his legs.  Which of the following is the most likely therapeutic mechanism of desmopressin for this patient's condition?

A) Binding to renal tubular cell receptors
B) Increase in endothelial protein release
C) Increase in liver protein synthesis
D) Inhibition of fibrinolysis
E) Vascular smooth muscle contraction

Correct Answer:

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