A 64-Year-Old Woman Is Hospitalized for Elective Hip Replacement Surgery

A 64-year-old woman is hospitalized for elective hip replacement surgery.  She has osteoarthritis and is experiencing progressive right hip pain that limits her daily activities.  The patient also has a history of hypertension and hypothyroidism.  Her blood pressure is 130/80 mm Hg and pulse is 90/min.  BMI is 31.5 kg/m².  Her serum creatinine is 0.9 mg/dL.  She undergoes surgery without complications and is postoperatively started on a medication that is a low molecular weight fraction of a negatively charged chemical stored in mast cell granules.  Which of the following is the most likely mechanism of action of the medication used?

A) Binds antithrombin III
B) Binds to the thrombin active site
C) Blocks ADP receptors
D) Combines with proactivator plasminogen
E) Inhibits arachidonate product formation

Correct Answer:

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