A 65-Year-Old Man Comes to the Office Due to Advanced

A 65-year-old man comes to the office due to advanced prostate cancer with bone metastases.  For the last 4 months, he has been treated with a GnRH agonist, which has significantly reduced his bone pain.  However, the patient now reports discomfort at the anterior chest wall.  Physical examination reveals bilateral, mildly tender enlargement of the breast tissue behind the nipple-areolar complex.  Early initiation of which of the following medications would be most appropriate for preventing this patient's breast symptoms?

A) Bicalutamide
B) Danazol
C) Finasteride
D) Spironolactone
E) Tamoxifen

Correct Answer:

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