A 50-Year-Old Man Is Brought to the ER with Severe

A 50-year-old man is brought to the ER with severe dizziness and confusion.  He states that he had an episode of chest pain and took several tablets of nitroglycerin.  His current medications include a daily aspirin for heart attack prevention, an occasional acetaminophen for headaches and occasionally tadalafil for erectile dysfunction.  His blood pressure is 50/20 mmHg and his heart rate is 120 beats/min.  Which of the following cellular changes is most likely responsible for this patient's symptoms?

A) Receptor downregulation
B) G_s protein phosphorylation
C) Cyclic GMP accumulation
D) Tyrosine kinase overactivity
E) Enhanced phospholipid metabolism
F) Tolerance development

Correct Answer:

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