Scientists Studying the Kidney's Response to Hypoperfusion Apply a Clip

Scientists studying the kidney's response to hypoperfusion apply a clip to a pig's right renal artery that reduces blood flow to the kidney by about 70%.  After 6 months, they perform a right nephrectomy and examine the glomeruli and tubules microscopically.  Which of the following cell types would be most likely to undergo hyperplasia as a result of the clip placement?

A) Cuboidal epithelial cells of the proximal tubules
B) Endothelial cells of the efferent arteriole
C) Intraglomerular mesangial cells
D) Modified smooth muscle cells of the afferent arteriole
E) Squamous epithelial cells of the thick ascending limb of the loop of Henle

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