A 2-Year-Old Child Is Brought to His Pediatrician Because of Failure

A 2-year-old child is brought to his pediatrician because of failure to thrive and polyuria.  He is found to have glucosuria on urinalysis, although his serum glucose is within normal limits.  What renal defect is responsible for his condition?

A) Necrosis of the renal papilla
B) Inflammation and fibrosis of the interstitium
C) Increased permeability of the glomerular membrane
D) Defect in proximal tubular reabsorption
E) Multiple cysts in the renal parenchyma

Correct Answer:

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