A 24-Year-Old Man Comes to the Office Due to Paroxysmal

A 24-year-old man comes to the office due to paroxysmal episodes of breathlessness and wheezing for the past 6 months.  He does not recognize any triggers for these episodes and reports they are not associated with exercise or stress.  The patient has no history of recent illness.  He had eczema as a child.  The patient has no other medical conditions and takes no medications.  Vital signs are within normal limits.  Lung examination shows good air movement and no wheezing.  Sputum microscopy reveals many granule-containing cells and crystalloid masses.  The sputum findings in this patient are a direct result of which of the following cytokines?

A) IL-1
B) IL-5
C) IL-12
D) Interferon-gamma
E) TGF-β

Correct Answer:

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