A 38-Year-Old Woman Is Being Evaluated for Intermittent Tingling and Numbness

A 38-year-old woman is being evaluated for intermittent tingling and numbness of the left hand for the past several months.  Her symptoms predominantly involve the fourth and fifth digits and are often brought on by driving a car.  Physical examination shows no abnormalities.  An electrodiagnostic study is performed, during which a nerve stimulator is placed on the left fifth digit and a surface recorder is placed over the ulnar nerve above the elbow.  Electrical stimulus is applied, and the graph obtained is shown below.  Results from the asymptomatic contralateral extremity are also shown.  Which of the following is primarily affected in this patient?

A) Neuronal axons
B) Neuronal cell bodies
C) Postsynaptic membrane
D) Schwann cells
E) Synaptic vesicles

Correct Answer:

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