A Researcher Is Exploring Various Methods to Decrease Neuronal Loss

A researcher is exploring various methods to decrease neuronal loss after ischemic injury.  During an experiment, the researcher induces focal cerebral ischemia in rodents; after a short time, there is ATP depletion and subsequent ionic derangements in cells within the infarction core.  Increased release and impaired clearance of extracellular neurotransmitters is also noted.  One particular neurotransmitter leads to sustained calcium influx in exposed neurons, initiating a toxic cascade that result in rapid cell death.  Blockade of a receptor for which of the following neurotransmitters is most likely to decrease this type of neuronal injury?

A) Dopamine
B) Glutamate
C) Glycine
D) Norepinephrine
E) Serotonin

Correct Answer:

Verified

Unlock this answer now
Get Access to more Verified Answers free of charge

Access For Free