A 32-Year-Old Woman Comes to the Office Due to Several

A 32-year-old woman comes to the office due to several days of fatigue and malaise.  She has no significant medical history and has had no recent sick contacts.  The patient does not appear to be in acute distress.  Evaluation reveals severe thrombocytopenia.  Thrombotic thrombocytopenic purpura is suspected.  Which of the following findings is required to make the diagnosis?

A) Abnormal neurologic examination
B) Elevated liver aminotransferases
C) Fever
D) Hemolytic anemia
E) Positive Coombs testing
F) Renal failure

Correct Answer:

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