A 54-Year-Old Man Comes to the Emergency Department with Pain

A 54-year-old man comes to the emergency department with pain and swelling in the right leg.  The patient has no other medical problems and takes no medications.  He has smoked a pack of cigarettes daily for the past 30 years.  He is a business executive and just returned from an overseas trip.  Physical examination shows pitting edema of the right leg and tenderness on deep palpation of the calf muscles.  Peripheral pulses are symmetric and full.  He is started on a medication that prolongs activated partial thromboplastin time and prothrombin time in a dose-dependent manner but has no effect on thrombin time.  Which of the following agents was this patient most likely administered?

A) Cyclooxygenase inhibitor
B) Direct factor VIIa inhibitor
C) Direct factor Xa inhibitor
D) Direct thrombin inhibitor
E) Unfractionated heparin

Correct Answer:

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