A 43-Year-Old Man Comes to the Office with a Several-Month

A 43-year-old man comes to the office with a several-month history of fatigue, rash, flushing, and abdominal cramps.  His rash is worse with rubbing or scratching, and he has diffuse itching after hot showers.  The patient is frequently dizzy and light-headed after prolonged standing and had an episode of syncope while working in the hot sun.  He used to be healthy and physically active but has had to reduce his normal activity.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are normal.  Skin examination shows a maculopapular rash.  Skin biopsy shows large clusters of mast cells that are positive for KIT (CD 117) .  Which of the following additional findings are most likely present in this patient?

A) Bacterial colonization of the stomach
B) Gastric atrophy
C) Gastric hypersecretion
D) Gastric hypomotility
E) Pancreatic endocrine tumor
F) Pernicious anemia

Correct Answer:

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