A Newborn Boy Who Was Born at 39 Weeks Gestation

A newborn boy who was born at 39 weeks gestation by normal vaginal delivery has a serum TSH above the normal range and serum thyroxine (T4) below the normal range for his age.  His mother has no medical conditions.  On examination, the patient's length and weight are normal, and he has no apparent congenital malformations.  Which of the following is the most likely cause of this patient's condition?

A) Central hypothyroidism
B) Generalized thyroid hormone resistance
C) Reduced thyroid-binding globulin
D) Thyroid dysgenesis
E) TSH receptor-stimulating antibodies

Correct Answer:

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