A 27-Year-Old Man Comes to the Office Due to Recurrent

A 27-year-old man comes to the office due to recurrent episodes of muscle weakness.  He has no other significant past medical history.  The patient's weight has been stable for the past few years, and his current BMI is 23 kg/m².  His blood pressure is 190/110 mm Hg supine and 195/110 mm Hg standing.  His heart rate is 70/min supine and 72/min standing.  The rest of the physical examination is unremarkable.  Laboratory evaluation shows very low plasma renin activity.  Overactivity of which of the following structures is most likely responsible for this patient's symptoms?

A) Chromaffin cells of the adrenals
B) Extra-adrenal paraganglion cells
C) Juxtaglomerular cells of the kidney
D) Zona fasciculata of the adrenals
E) Zona glomerulosa of the adrenals
F) Zona reticularis of the adrenals

Correct Answer:

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