A Researcher Studying the Cell Cycle Observes a Sudden Increase

A researcher studying the cell cycle observes a sudden increase in the activity of several enzymes, including dihydrofolate reductase and DNA polymerase.  Which of the following processes most immediately precedes the observed increase in enzyme activity?

A) Caspase enzyme cleavage
B) GDP binding to Ras protein
C) p27 protein upregulation
D) Protein kinase A phosphorylation
E) Retinoblastoma protein phosphorylation

Correct Answer:

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