An 8-Year-Old Boy Is Being Evaluated Due to Drug-Resistant Epilepsy

An 8-year-old boy is being evaluated due to drug-resistant epilepsy.  The patient has had recurrent seizures since age 2, which have remained uncontrolled despite multiple antiepileptic medications.  He has no history of head trauma, meningitis, or encephalitis.  There is no family history of seizure disorder.  Electroencephalography reveals epileptic foci originating from the left temporal lobe, and neuroimaging reveals an abnormality of the left hippocampus.  Surgical resection of the cortical region from which the seizure originates is performed.  Histopathological examination of the removed brain tissue is most likely to reveal which of the following findings?

A) Astrocytic proliferation
B) Hemosiderin-laden macrophages
C) Microglial nodules
D) Neuronal inclusion bodies
E) Spongiform changes

Correct Answer:

Verified

Unlock this answer now
Get Access to more Verified Answers free of charge

Access For Free