A 24-Year-Old Man Comes to the Physician with Complaints of Tinnitus

A 24-year-old man comes to the physician with complaints of tinnitus, vertigo, and hearing loss.  A contrast-enhanced, T1-weighted image of his brain is shown below. This patient's condition is most likely associated with a mutation involving which of the following genes?

A) APC on chromosome 5
B) NF1 on chromosome 17
C) NF2 on chromosome 22
D) p53 on chromosome 17
E) RB1 on chromosome 13
F) VHL on chromosome 3

Correct Answer:

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