A 12-Year-Old Boy Is Brought to the Emergency Room Due

A 12-year-old boy is brought to the emergency room due to high fever, chest pains, and dyspnea.  Medical history is significant for 2 prior hospitalizations for abdominal pain that resolved with analgesics and hydration.  Evaluation today shows a hematocrit of 23% and reticulocyte count of 9%.  Several hours after being admitted to the hospital, the patient dies.  At autopsy, the spleen is small and firm.  This patient's autopsy finding is most likely related to which of the following?

A) Extramedullary hematopoiesis
B) Follicular hyperplasia
C) Lipid accumulation
D) Pressure atrophy
E) Vascular occlusion

Correct Answer:

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