A 46-Year-Old Woman Comes to the Office with Persistent Diarrhea

A 46-year-old woman comes to the office with persistent diarrhea, weight loss, and abdominal pain.  Her diarrhea started several months ago.  She has no fever, melena, or hematochezia.  The patient has not traveled outside of the country and has not drunk from any untreated freshwater sources.  She has had no recent hospitalizations or antibiotic use.  Her sister has a history of celiac disease.  Upper endoscopy reveals postbulbar duodenal and jejunal ulcers.  This patient most likely has a tumor secreting which of the following molecules?

A) Gastrin
B) Glucagon
C) Insulin
D) Serotonin
E) Somatostatin
F) Vasoactive intestinal polypeptide

Correct Answer:

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