A 59-Year-Old Man Is Evaluated in the Clinic for Recent

A 59-year-old man is evaluated in the clinic for recent unintentional weight loss.  He says, "My pants are fitting a lot looser than usual."  The patient also has epigastric discomfort after meals with occasional nausea.  He reports that food is not as appetizing as it used to be.  He has no known medical conditions and takes no medications.  The patient's father has a history of peptic ulcer disease.  Upper endoscopy shows a lesion in the stomach that is biopsied; a histologic section is shown below: This patient's lesion is most likely to demonstrate which of the following gross findings?

A) Deep ulceration and vessel erosion
B) Infiltrative growth within the stomach wall
C) Progressive mucosal atrophy
D) Rapid intraluminal expansion
E) Rugal thickening with acid hypersecretion

Correct Answer:

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