A 65-Year-Old Woman Comes to the Office After Finding Blood

A 65-year-old woman comes to the office after finding blood in her stool.  She is physically active and exercises regularly.  She does not use tobacco or alcohol.  She has no history of peptic ulcer disease.  Her physical examination is unremarkable.  Colonoscopy reveals several large adenomatous polyps with severe dysplasia in the sigmoid colon.  She undergoes resection of the sigmoid colon, and her carcinoembryonic antigen level is normal.  The patient is interested in decreasing her chances of developing new polyps and colon cancer.  The physician discusses exercise, healthy weight, and dietary factors associated with reduction of colon cancer risk, including increased fiber intake and reduced consumption of refined sugars and fat.  Which of the following enzymes could be inhibited with medication to further reduce this patient's risk of developing recurrent adenoma?

A) Angiotensin-converting enzyme
B) Caspase
C) Cyclooxygenase-2
D) Glutamate dehydrogenase
E) Phenylalanine hydroxylase
F) Xanthine oxidase

Correct Answer:

Verified

Unlock this answer now
Get Access to more Verified Answers free of charge

Access For Free