A 46-Year-Old Man Comes to the Office with the Skin

A 46-year-old man comes to the office with the skin lesions shown in the photograph below.  The patient first noticed the lesions a week ago after he returned from a trip to Hawaii.  He has not had any other significant rashes or skin lesions but does have a history of autoimmune thyroiditis. Which of the following would most likely be seen on histopathologic examination of this patient's lesions?

A) Absence of melanocytes in the epidermis
B) Linear pattern of melanocyte proliferation
C) Melanosome aggregates within the cytoplasm of melanocytes
D) Normal melanocytes with diminished pigment transfer to keratinocytes
E) Poor melanin formation in melanocytes

Correct Answer:

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