A 64-Year-Old Man Comes to the Physician with Several Lesions

A 64-year-old man comes to the physician with several lesions on his forehead.  The patient has been a gardener for much of his life.  The photograph below shows findings from the physical examination. On palpation, the lesions have a rough grainy texture.  Biopsy reveals atypical keratinocytes with hyperkeratosis and parakeratosis.  This patient's lesions put him at greatest risk for developing which of the following conditions?

A) Basal cell carcinoma
B) Dermatofibroma
C) Kaposi sarcoma
D) Melanoma
E) Psoriasis
F) Squamous cell carcinoma

Correct Answer:

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