A 62-Year-Old Man Dies Suddenly in His Sleep

A 62-year-old man dies suddenly in his sleep.  The patient had a history of type 2 diabetes mellitus and hypertension, and he smoked a pack of cigarettes daily for 25 years.  His adherence to medical care was poor.  Autopsy is performed, and a histologic section of his left ventricular myocardium is shown below: Which of the following directly promotes the formation of the tissue indicated by the arrow?

A) Endothelium-derived relaxing factor
B) Interferon-beta
C) Interleukin-8
D) Transforming growth factor-beta
E) Tumor necrosis factor-alpha

Correct Answer:

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