A 45-Year-Old Man Comes to the Office Due to a Sore

A 45-year-old man comes to the office due to a sore throat for the past 3 months.  The patient also has pain with swallowing.  He has never smoked, drinks alcohol occasionally, and does not use illicit drugs.  On physical examination, the right tonsil is enlarged with a small area of ulceration.  The rest of the physical examination is unremarkable.  Biopsy of the right tonsil is shown in the image below: Which of the following most likely played the most significant role in the pathogenesis of this patient's condition?

A) Coxsackievirus
B) Epstein-Barr virus
C) Herpes simplex virus
D) Human immunodeficiency virus
E) Human papilloma virus

Correct Answer:

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