A Previously Healthy 27-Year-Old Man Comes to the Clinic Due

A previously healthy 27-year-old man comes to the clinic due to fever and rash.  The patient is a missionary who recently immigrated from South Africa with his wife and 3 young children.  Four days ago, he developed a high fever and malaise followed by the appearance of multiple discrete macules on his face, trunk, and extremities.  The lesions are pruritic and evolved into pustules then vesicles.  The patient has continued to develop new vesicles as other lesions crust over and heal.  The remainder of the examination is unremarkable.  This patient's symptoms are most likely due to an infection with which of the following pathogens?

A) Coxsackievirus
B) Herpes simplex virus
C) Human herpesvirus 6
D) Parvovirus
E) Varicella-zoster virus
F) Variola virus

Correct Answer:

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