Immunoglobulins of Different Classes Have Different Structures

Immunoglobulins of different classes have different structures.  Some immunoglobulins have long hinge regions between the Fab and Fc regions, whereas others lack the hinge region, as shown in the image below: The hinge region provides movement flexibility to the Fab regions.  This is most likely to affect which of the following immunoglobulin properties?

A) Affinity to antigen
B) Antibody polymerization
C) Avidity to antigen
D) Effector cell interaction
E) Effector cell specificity

Correct Answer:

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