A 7-Year-Old Boy Is Brought to the Office Due to Sudden

A 7-year-old boy is brought to the office due to sudden onset of facial swelling 2 hours ago.  He has had no itching or pain other than a sore throat over the last 2 days, for which he has taken acetaminophen.  The patient has had similar episodes of facial swelling that resolved spontaneously after a few days.  Temperature is 37 C (98.6 F) , blood pressure is 100/78 mm Hg, pulse is 95/min, and respirations are 24/min.  Examination shows nonpitting edema of the cheeks, lips, and tongue; there is no tenderness or erythema.  Which of the following studies is most likely to be abnormal?

A) Eosinophil count
B) Serum C4 level
C) Serum C8 level
D) Serum IgA level
E) Serum IgE level

Correct Answer:

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