A Study Is Performed to Compare the Effect of Tramadol

A study is performed to compare the effect of tramadol when compared to placebo for painful polyneuropathy.  Fifty patients are selected and randomly allocated to 1 of 2 treatment sequences:  Tramadol followed by placebo, or placebo followed by tramadol.  The initial treatment period is delivered for 4 weeks followed by an interim 1-week washout phase, after which the second treatment period is delivered for an additional 4 weeks.  After each treatment period, patients use a 10-point numeric scale to rate pain, paresthesia, and tenderness.  Which of the following best describes this study design?

A) Case-control study
B) Case series study
C) Crossover study
D) Cross-sectional study
E) Prospective cohort study
F) Retrospective cohort study

Correct Answer:

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