Researchers Are Developing an Enzyme-Linked Immunosorbent Assay Test for Diagnosing

Researchers are developing an enzyme-linked immunosorbent assay test for diagnosing rheumatoid arthritis.  The test is designed to detect the presence of serum antibodies against citrullinated proteins.  Two test populations with a differing prevalence of rheumatoid arthritis are selected.  The researchers plan to assess the test's performance in the 2 populations by comparing a number of diagnostic test parameters.  Which of the following performance measures is most likely to be different between the 2 test populations?

A) Negative likelihood ratio
B) Positive likelihood ratio
C) Positive predictive value
D) Sensitivity
E) Specificity

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