A Research Scientist Develops an Agent That Specifically Blocks the Interaction

A research scientist develops an agent that specifically blocks the interaction of inositol triphosphate with its intracellular receptor.  A study is then performed in which vascular smooth muscle cells are divided into 2 groups: an experimental group treated with the receptor blocker and an untreated control group.  Both groups are exposed to phenylephrine.  Compared to the control cells, decreased activity of which of the following enzymes is most likely to be observed in the experimental cells?

A) Adenylate cyclase
B) Lipoxygenase
C) Phosphodiesterase
D) Phospholipase C
E) Protein kinase C

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