A 54-Year-Old Man Is Evaluated for Episodic Abdominal Discomfort, Bloating

A 54-year-old man is evaluated for episodic abdominal discomfort, bloating sensation, flatulence, and occasional diarrhea.  He has no blood in the stool or weight loss.  The patient has tried avoiding dairy products, but the symptoms did not improve.  On examination, there is mild epigastric tenderness on deep palpation.  Stool occult blood testing is positive.  Histopathological evaluation of hyperemic mucosa seen during gastrointestinal endoscopy reveals hyperplasia of branched, tubular submucosal glands containing alkaline secretions.  Which of the following areas is the most likely site of biopsy in this patient?

A) Antrum of the stomach
B) First part of the duodenum
C) Fundus of the stomach
D) Mid-part of the jejunum
E) Terminal ileum
F) Transverse colon

Correct Answer:

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