Which of the Following Resulted in the First Demonstration of Artificial

Which of the following resulted in the first demonstration of artificial transmutation?

A) Rutherford's bombardment of nitrogen-14 with alpha particles
B) Fermi and Segre's bombardment of uranium atoms with neutrons
C) the change of lead into gold by alchemists in the 14th century
D) Goldstein's production of protons in a gas discharge tube

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