Soon After the Discovery of Nerve Growth Factor (NGF), Researchers

Soon after the discovery of nerve growth factor (NGF) , researchers injected newborn mice with rabbit antiserum (i.e. serum that contains antibodies) against NGF. They observed massive nerve cell death compared to appropriate control injections. Up to 99% of the neurons in some parts of the developing peripheral nervous system died after about a week of daily injections. These results suggest that ...

A) NGF signaling sensitizes developing nerve cells to apoptotic signals.
B) developing neurons undergo apoptosis in the presence of rabbit proteins.
C) developing neurons require NGF for apoptosis.
D) developing neurons undergo cell death in the absence of NGF.
E) NGF signaling is sufficient for survival of the developing neurons.

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