How Does the Toxin from Clostridium Tetani Produce Its Action

How does the toxin from Clostridium tetani produce its action?

A) it fuses irreversibly to neurons, blocking release of acetylcholine at synaptic clefts.
B) the smaller polypeptide of its toxin can block the release of inhibitory neurotransmitters by inhibitory neurons in the central nervous system.
C) it is a pyrogenic toxin, which triggers a diffused rash and, later, sloughing of skin.
D) it destroys tissues, including muscle and fat.
E) Antibodies to the toxin bind the neuromuscular junctions in skeletal muscle preventing relaxation.

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