A Phenotypically Normal Couple Seeks Genetic Counseling Because the Man's

A phenotypically normal couple seeks genetic counseling because the man's karyotype showed that his chromosomes had a reciprocal translocation between chromosomes 4 and 12. Because the translocation is reciprocal there was no genetic information lost and he is healthy; however, he and his wife want to know the probability that his sperm cells will be abnormal. Which fraction of his sperm cells is predicted to carry at least one chromosome with a translocation?

A) three-fourth will have at least one chromosome with a translocation; the other 1/4 will carry normal chromosomes 4 and 12
B) all will carry the same translocation as the father
C) none will carry the translocation
D) one-half will have the father's translocation and 1/2 will carry normal chromosomes 4 and 12

Correct Answer:

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