Which Statement Best Supports the Hypothesis That Glycolysis Is an Ancient

Which statement best supports the hypothesis that glycolysis is an ancient metabolic pathway that originated before the last universal common ancestor of life on Earth?

A) Glycolysis is widespread and is found in the domains Bacteria, Archaea, and Eukarya.
B) Glycolysis neither uses nor needs O₂.
C) Glycolysis is found in all eukaryotic cells.
D) The enzymes of glycolysis are found in the cytosol rather than in a membrane-enclosed organelle.
E) Ancient prokaryotic cells, the most primitive of cells, made extensive use of glycolysis long before oxygen was present in Earth's atmosphere.

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